Immunological Sciences

PDX1 Mouse Monoclonal Antibody

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Catalog Number:MABN81109
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human PDX1 expressed in E. Coli.
Reactivity:Human
Applications:ELISA 1:5000-1:20000,FC 1:200-1:400
Molecular Weight:30.8kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:GSF; IPF1; IUF1; IDX-1; MODY4; PDX-1; STF-1

Applications

ELISA 1:5000-1:20000,FC 1:200-1:400

Immunogen

Purified recombinant fragment of human PDX1 expressed in E. Coli.

Target Background

The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

Synonyms:GSF; IPF1; IUF1; IDX-1; MODY4; PDX-1; STF-1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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