PE Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]
![Staining of C57BL/6 murine splenocytes with APC Anti-Mouse CD3 Antibody[17A2] and PE Anti-Mouse CD274/PD-L1 Antibody[10F.9G2] (left) or PE Rat IgG2b, κ Isotype Control (right). Total viable cells were used for analysis.](/storage/products/wp-images/2026/01/product_394_img_1.jpg)
Staining of C57BL/6 murine splenocytes with APC Anti-Mouse CD3 Antibody[17A2] and PE Anti-Mouse CD274/PD-L1 Antibody[10F.9G2] (left) or PE Rat IgG2b, κ Isotype Control (right). Total viable cells were used for analysis.
| Catalog Number: | MAB1132D |
| Conjugate: | PE |
| Size: | 100Tests |
| Concentration: | 5 μL/Test |
| Host: | Rat |
| Isotype: | Rat IgG2b, κ |
| Clone: | Monoclonal |
| Reactivity: | Mouse |
| Applications: | Each lot of this antibody is quality control tested by flow cytometric analysis. <b style="color:#0070ca">The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood).</b> Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
| Form: | Liquid |
| Synonyms: | PD-;B7h1;Pdl1;Pdcd1l;Pdcd1l1;Pdcd1lg1;A530045L16Rik;Cd274 |
CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-γ, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.
Applications
Each lot of this antibody is quality control tested by flow cytometric analysis. <b style="color:#0070ca">The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood).</b> Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.