PerCP/Cyanine5.5 Anti-Human/Monkey CD27 Antibody[O323]
Human peripheral blood lymphocytes are stained with FITC Anti-Human CD19 Antibody and PerCP/Cyanine5.5 Anti-Human/Monkey CD27 Antibody (Left). Lymphocytes are stained with FITC Anti-Human CD19 Antibody and PerCP/Cyanine5.5 Mouse IgG1, κ Isotype Control (Right).
| Catalog Number: | MAB1140J |
| Conjugate: | PerCP/Cyanine5.5 |
| Size: | 100 tests |
| Host: | Mouse |
| Isotype: | Mouse IgG1, κ |
| Clone: | O323 |
| Reactivity: | Human,Rhesus |
| Applications: | FCM: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
| Molecular Weight: | 50-55 kD |
| Form: | Liquid |
| Synonyms: | CD27L receptor,S152,T-cell activation antigen CD27,T14,TNFRSF7 |
CD27 is a 50-55 kD type I membrane protein also known as S152 and T14. It is a lymphocyte-specific member of the TNF-receptor superfamily. CD27 is expressed on medullary thymocytes, virtually all mature T cells, some B cells, and NK cells. CD27 binds to CD70 and plays an important role in costimulation of T cell activation, and regulation of B cell differentiation and proliferation. The cytoplasmic domains of CD27 have also been shown to interact with TRAF2 and TRAF5 to elicit NF-κB and SAPK/JNK activation.
Applications
FCM: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.