Immunological Sciences

Peroxiredoxin 4 (1T10) Rabbit Monoclonal Antibody

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Catalog Number:MABN15993
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Peroxiredoxin 4
Reactivity:Human,Mouse,Rat
Applications:WB 1:2000-1:20000,IHC 1:100-1:200,IF-P 1:100-1:200
Molecular Weight:31kDa
Purification:Affinity purification
Form:Liquid
Synonyms:AOE37-2; PRX-4;

Applications

WB 1:2000-1:20000,IHC 1:100-1:200,IF-P 1:100-1:200

Immunogen

A synthetic peptide of human Peroxiredoxin 4

Target Background

Probably involved in redox regulation of the cell. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation. Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.

Synonyms:AOE37-2; PRX-4;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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