Immunological Sciences

PEX19 (2Y10) Rabbit Monoclonal Antibody

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Catalog Number:MABN16002
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human PEX19
Reactivity:Human,Rat
Applications:WB 1:1000-1:5000,ICC/IF 1:50-1:100,FC 1:10-1:100,IP 1:10-1:100
Molecular Weight:33kDa
Purification:Affinity purification
Form:Liquid
Synonyms:HK33; PBD12A; Peroxin 19; PEX19; PMP1; PMPI; PXF; PXMP1;

Applications

WB 1:1000-1:5000,ICC/IF 1:50-1:100,FC 1:10-1:100,IP 1:10-1:100

Immunogen

A synthetic peptide of human PEX19

Target Background

Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.

Synonyms:HK33; PBD12A; Peroxin 19; PEX19; PMP1; PMPI; PXF; PXMP1;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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