Immunological Sciences

PGC1 beta (19E7) Rabbit Monoclonal Antibody

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Catalog Number:MABN16024
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human PGC1 beta
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IP 1:10-1:100
Molecular Weight:113kDa
Purification:Affinity purification
Form:Liquid
Synonyms:PERC; PGC1; PPARGC1; Ppargc1b;

Applications

WB 1:1000-1:5000,IP 1:10-1:100

Immunogen

A synthetic peptide of human PGC1 beta

Target Background

Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcriptional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non- oxidative glucose metabolism and in the regulation of energy expenditure. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.

Synonyms:PERC; PGC1; PPARGC1; Ppargc1b;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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