Immunological Sciences

PGP9.5 (5O2) Rabbit Monoclonal Antibody

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Catalog Number:MABN16043
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human PGP9.5
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:50-1:100
Molecular Weight:25kDa
Purification:Affinity purification
Form:Liquid
Synonyms:UCH-L1; PGP9.5; UCHL1;

Applications

WB 1:1000-1:5000,IHC 1:50-1:100

Immunogen

A synthetic peptide of human PGP9.5

Target Background

Involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins (Probable). This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin (PubMed:9774100, PubMed:8639624, PubMed:12408865, PubMed:23359680). Also binds to free monoubiquitin and may prevent its degradation in lysosomes (By similarity). The homodimer may have ATP-independent ubiquitin ligase activity (PubMed:12408865).

Synonyms:UCH-L1; PGP9.5; UCHL1;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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