Immunological Sciences

Phospho-4E-BP1 (Ser65) Mouse Monoclonal Antibody

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Catalog Number:MABN81829
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Synthesized peptide of human Phospho-4E-BP1 (Ser65).
Reactivity:Human
Applications:IHC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400
Molecular Weight:12.6kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:EIF4EBP1; BP-1; 4EBP1; 4E-BP1; PHAS-I

Applications

IHC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400

Immunogen

Synthesized peptide of human Phospho-4E-BP1 (Ser65).

Target Background

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Synonyms:EIF4EBP1; BP-1; 4EBP1; 4E-BP1; PHAS-I

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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