Immunological Sciences

Phospho-AKT1 (S124) (4J11) Rabbit Monoclonal Antibody

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Catalog Number:MABN05846
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic phosphopeptide corresponding to residues surrounding Ser124 of human AKT1
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IP 1:50-1:200
Molecular Weight:56kDa
Purification:Affinity purification
Form:Liquid
Synonyms:AKT 1; PKB; PKB-ALPHA; PRKBA; Protein Kinase B Alpha; Protein kinase B; Proto-oncogene c-Akt; RAC Alpha;

Applications

WB 1:500-1:2000,IP 1:50-1:200

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser124 of human AKT1

Target Background

Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473.

Synonyms:AKT 1; PKB; PKB-ALPHA; PRKBA; Protein Kinase B Alpha; Protein kinase B; Proto-oncogene c-Akt; RAC Alpha;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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