Immunological Sciences

Phospho-AMPK alpha 1 (Thr183)/AMPK alpha 2 (Thr172) Rabbit Monoclonal Antibody

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Catalog Number:MABN87121
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic phosphopeptide corresponding to residues surrounding Thr183/Thr172 of human AMPK alpha 1/AMPK alpha 2
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000
Molecular Weight:Calculated MW:64,62 kDa; Observed MW:62 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:AMPK; AMPKa1

Applications

WB 1:1000-1:5000

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Thr183/Thr172 of human AMPK alpha 1/AMPK alpha 2

Target Background

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

Synonyms:AMPK; AMPKa1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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