Phospho-AMPKα1/2 (T183/172)

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Catalog Number:ABP-0432
Conjugate:Unconjugated
Size:100 ug
Concentration:1mg/ml
Host:Rb
Isotype:IgG
Clone:Poly
Immunogen:A phospho specific peptide corresponding to residues surrounding T172 of human AMPKα
Reactivity:Hu, Ms, Rt
Applications:WB
Molecular Weight:64kDa
Purification:Affinity purification
Form:liquid
Synonyms:AMPKa1/AMPKa2

Applications

WB

Immunogen

A phospho specific peptide corresponding to residues surrounding T172 of human AMPKα

Target Background

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is thecatalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellularenergy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activatedby the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of anumber of key metabolic enzymes through phosphorylation. It protects cells fromstresses that cause ATP depletion by switching off ATP-consuming biosyntheticpathways. Alternatively spliced transcript variants encoding distinct isoforms have beenobserved. [provided by RefSeq, Jul 2008]

Synonyms:AMPKa1/AMPKa2

Storage

Store at -20℃. Avoid freeze / thaw cycles

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

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