Immunological Sciences

Phospho-ATF4 (Ser219) Rabbit Polyclonal Antibody

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Catalog Number:ABN00926
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:A synthetic Phosphorylated peptide corresponding to residues target protein
Reactivity:Human
Applications:WB 1:500-1:1000
Molecular Weight:Calculated MW: 39 kDa; Observed MW: 39 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Cyclic AMP-dependent transcription factor ATF-4; CREB-2; cAMP-responsive element-binding protein 2; DNA-binding protein TAXREB67

Applications

WB 1:500-1:1000

Immunogen

A synthetic Phosphorylated peptide corresponding to residues target protein

Target Background

ATF4, an activating transcription factor/cAMP-response element-binding protein family member, functions in the PERK and eIF2α ER stress responsive pathway. ER stress represses the translation of the majority of mRNAs, but selectively stimulates the translation of certain mRNAs including that of ATF-4. Induced expression of ATF-4 increases the expression of genes critical for the recovery from ER stress.

Synonyms:Cyclic AMP-dependent transcription factor ATF-4; CREB-2; cAMP-responsive element-binding protein 2; DNA-binding protein TAXREB67

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

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