Immunological Sciences

Phospho-ATP Citrate Synthase (Thr447/Ser451) Rabbit Monoclonal Antibody

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Catalog Number:MABN01694
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic Phosphorylated peptide corresponding to residues target protein
Reactivity:Human
Applications:WB 1:500-1:1000
Molecular Weight:Calculated MW: 121 kDa; Observed MW: 121 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ACLY; ATP-citrate synthase; ATP-citrate; pro-S-)-lyase; ACL; Citrate cleavage enzyme

Applications

WB 1:500-1:1000

Immunogen

A synthetic Phosphorylated peptide corresponding to residues target protein

Target Background

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis.

Synonyms:ACLY; ATP-citrate synthase; ATP-citrate; pro-S-)-lyase; ACL; Citrate cleavage enzyme

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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