Phospho-Bcl-2 (Ser70) Rabbit Monoclonal Antibody

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Catalog Number:MABN87122
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic phosphopeptide corresponding to residues surrounding Ser70 of human Bcl-2
Reactivity:Human
Applications:WB 1:500-1:2000,ICC/IF 1:500-1:1000,FC 1:200-1:500,IP 1:20-1:50
Molecular Weight:Calculated MW:26 kDa; Observed MW:26 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Bcl-2; PPP1R50

Applications

WB 1:500-1:2000,ICC/IF 1:500-1:1000,FC 1:200-1:500,IP 1:20-1:50

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser70 of human Bcl-2

Target Background

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

Synonyms:Bcl-2; PPP1R50

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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