Immunological Sciences

Phospho-Caspase-3 (S150)

Western Blot (WB) analysis of HBE using p-Caspase-3 (S150) antibody

Western Blot (WB) analysis of HBE using p-Caspase-3 (S150) antibody

Catalog Number:ABP10164
Conjugate:Unconjugated
Size:100 ug
Concentration:1mg/ml
Host:Rb
Isotype:IgG
Clone:Poly
Immunogen:Synthesized peptide derived from human Caspase-3 around the phosphorylation site of S150.
Reactivity:Human, Mouse, Rat
Applications:Western Blot: 1:500-1:2000 Immunohistochemistry: 1:100-1:300 ELISA: 1:40000
Molecular Weight:34 kDA
Purification:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form:liquid
Synonyms:Caspase-3 CASP-3 Apopain Cysteine protease CPP32 CPP-32 Protein Yama SREBP cleavage activity 1 SCA-1 Caspase-3 subunit p17 Caspase-3 subunit P12

Applications

Western Blot: 1:500-1:2000 Immunohistochemistry: 1:100-1:300 ELISA: 1:40000

Immunogen

Synthesized peptide derived from human Caspase-3 around the phosphorylation site of S150.

Target Background

Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADPribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.

Synonyms:Caspase-3 CASP-3 Apopain Cysteine protease CPP32 CPP-32 Protein Yama SREBP cleavage activity 1 SCA-1 Caspase-3 subunit p17 Caspase-3 subunit P12

Storage

Store at -20°C, and avoid repeat freeze-thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Western Blot (WB) analysis of HBE using p-Caspase-3 (S150) antibody

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