Immunological Sciences

Phospho-Catenin-β (S33)

Western blot analysis of extracts from MCF-7 cells using Phospho-CTNNB1-S33 Antibody

Western blot analysis of extracts from MCF-7 cells using Phospho-CTNNB1-S33 Antibody

Catalog Number:ABP-0216
Conjugate:Unconjugated
Size:100 ug
Concentration:1mg/ml
Host:Rb
Isotype:IgG
Clone:Poly
Immunogen:A phospho specific peptide corresponding to residues surrounding S33 of human CTNNB1
Reactivity:Hu, Ms, Rt
Applications:WB 1:1000
Molecular Weight:92 kDa
Form:liquid
Synonyms:CTNNB; MRD19; armadillo

Applications

WB 1:1000

Immunogen

A phospho specific peptide corresponding to residues surrounding S33 of human CTNNB1

Target Background

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.

Synonyms:CTNNB; MRD19; armadillo

Storage

Store at -20° C. Avoid freeze / thaw cycles.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Western blot analysis of extracts from MCF-7 cells using Phospho-CTNNB1-S33 Antibody

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