Immunological Sciences

Phospho-Caveolin-2 (Y27)

Western Blot Image using ABP10182 Phospho-Caveolin-2 (Y27) antibody

Western Blot Image using ABP10182 Phospho-Caveolin-2 (Y27) antibody

Catalog Number:ABP10182
Conjugate:Unconjugated
Size:100 ug
Concentration:1mg/ml
Host:Rb
Isotype:IgG
Clone:Poly
Immunogen:Synthesized peptide derived from human Caveolin-2 around the phosphorylation site of Y27.
Reactivity:Hu
Applications:Western Blot: 1:500-1:2000ELISA 1:10000
Molecular Weight:26kDa
Purification:The antibody was affinity-purified from rabbit antiserum by affinitychromatography using epitope-specific immunogen.
Form:liquid

Applications

Western Blot: 1:500-1:2000ELISA 1:10000

Immunogen

Synthesized peptide derived from human Caveolin-2 around the phosphorylation site of Y27.

Target Background

May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression .Phospho-Caveolin-2 (Y27) Polyclonal Antibody detects endogenous levels of Caveolin-2 protein only when phosphorylated at Y27.

Storage

Store at -20℃. Avoid freeze / thaw cycles.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Western Blot Image using ABP10182 Phospho-Caveolin-2 (Y27) antibody

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