Immunological Sciences

Phospho-CD3 zeta (Tyr142) Rabbit Monoclonal Antibody

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Catalog Number:MABN84857
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic phosphopeptide corresponding to residues surrounding Tyr142 of human CD3 zeta
Reactivity:Human
Applications:WB 1:500-1:1000,IP 1:10-1:20
Molecular Weight:Calculated MW: 19 kDa; Observed MW: 19 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CD247; CD3Z; T3Z; TCRZ; T-cell surface glycoprotein CD3 zeta chain; T-cell receptor T3 zeta chain; CD antigen CD247

Applications

WB 1:500-1:1000,IP 1:10-1:20

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Tyr142 of human CD3 zeta

Target Background

Defects in CD3D are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (T(-)/B(+)/NK(+) SCID) [MIM:608971]. A form of severe combined immunodeficiency (SCID), a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels.

Synonyms:CD247; CD3Z; T3Z; TCRZ; T-cell surface glycoprotein CD3 zeta chain; T-cell receptor T3 zeta chain; CD antigen CD247

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

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