Phospho-CDC6 (Ser106) Rabbit Monoclonal Antibody

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Catalog Number:MABN84858
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic phosphopeptide corresponding to residues surrounding Ser106 of human Cdc6
Reactivity:Human,Rat
Applications:WB 1:500-1:1000
Molecular Weight:Calculated MW: 63 kDa; Observed MW: 63 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CDC6; CDC18L; Cell division control protein 6 homolog; CDC6-related protein; Cdc18-related protein; HsCdc18; p62(cdc6); HsCDC6

Applications

WB 1:500-1:1000

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser106 of human Cdc6

Target Background

Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.Cdc6 has recently been shown to play an important role in the intra-S-phase p21 Waf1/Cip1-dependent DNA damage response. Both cdc6 and CDT1 are degraded by the ubiquitin proteasome pathway in response to DNA damage associated with re-replication.

Synonyms:CDC6; CDC18L; Cell division control protein 6 homolog; CDC6-related protein; Cdc18-related protein; HsCdc18; p62(cdc6); HsCDC6

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

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