Phospho-Dishevelled 2 (Ser143) Rabbit Monoclonal Antibody

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Catalog Number:MABN84862
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic phosphopeptide corresponding to residues surrounding Ser143 of human Dishevelled 2
Reactivity:Human,Mouse
Applications:WB 1:500-1:1000
Molecular Weight:Calculated MW: 79 kDa; Observed MW: 90-95 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:DSH homolog 2

Applications

WB 1:500-1:1000

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser143 of human Dishevelled 2

Target Background

Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Participates both in canonical and non-canonical Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling.

Synonyms:DSH homolog 2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

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