Phospho-eIF4B (Ser406) Rabbit Monoclonal antibody

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Catalog Number:MABN02848
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic phosphopeptide corresponding to residues surrounding Ser406 of human eIF4B
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:1000,IHC 1:50-1:100
Molecular Weight:Calculated MW: 69 kDa; Observed MW: 80 kDa
Purification:Affinity Purified
Form:Liquid
Synonyms:EIF-4B; PRO1843

Applications

WB 1:500-1:1000,IHC 1:50-1:100

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser406 of human eIF4B

Target Background

The eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA.It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. It promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both eIF4A and eIF4F

Synonyms:EIF-4B; PRO1843

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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