Immunological Sciences

Phospho-GCN2 (Thr667) Rabbit Polyclonal Antibody

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Catalog Number:ABN00717
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:A synthetic Phosphorylated peptide corresponding to residues target protein
Reactivity:Human
Applications:WB 1:500-1:1000,IP 1:20-1:50
Molecular Weight:Calculated MW: 187 kDa; Observed MW: 220 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:GCN2-like protein; GCN2; KIAA1338; EIF2AK4

Applications

WB 1:500-1:1000,IP 1:20-1:50

Immunogen

A synthetic Phosphorylated peptide corresponding to residues target protein

Target Background

This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2.

Synonyms:GCN2-like protein; GCN2; KIAA1338; EIF2AK4

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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