Phospho-GSK3 (Tyr279/Tyr216) Rabbit Polyclonal Antibody

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Catalog Number:ABN00953
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:A synthetic Phosphorylated peptide corresponding to residues target protein
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:100-1:200
Molecular Weight:Calculated MW: 51 kDa; Observed MW: 46,51 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Serine/threonine-protein kinase GSK3A

Applications

WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:100-1:200

Immunogen

A synthetic Phosphorylated peptide corresponding to residues target protein

Target Background

GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.

Synonyms:Serine/threonine-protein kinase GSK3A

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

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