Phospho-Histone H2A.X (Ser139) (2A9) Mouse Monoclonal Antibody

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Catalog Number:MABN03679
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:IgG2a
Clone:Monoclonal
Immunogen:A synthetic Phosphorylated peptide corresponding to residues target protein
Reactivity:Human,Mouse
Applications:WB 1:500-1:1000,ICC/IF 1:50-1:200
Molecular Weight:Calculated MW: 15 kDa; Observed MW: 15 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:H2A.X; H2AFX; H2a/x; HIST5-2AX; Histone H2A.X; gamma H2A.X

Applications

WB 1:500-1:1000,ICC/IF 1:50-1:200

Immunogen

A synthetic Phosphorylated peptide corresponding to residues target protein

Target Background

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.

Synonyms:H2A.X; H2AFX; H2a/x; HIST5-2AX; Histone H2A.X; gamma H2A.X

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

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