Phospho-Histone H2A.X (Ser139) Mouse Monoclonal Antibody

No images available

Catalog Number:MABN84923
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Synthetic phosphopeptide corresponding to residues surrounding Ser139 of human H2A.X.
Reactivity:Human,Mouse
Applications:WB 1:500-1:1000,ICC 1:50-1:200
Molecular Weight:Calculated MW: 15 kDa; Observed MW: 15 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:H2A.X; H2AFX; H2a/x; HIST5-2AX; Histone H2A.X; gamma H2A.X

Applications

WB 1:500-1:1000,ICC 1:50-1:200

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding Ser139 of human H2A.X.

Target Background

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.

Synonyms:H2A.X; H2AFX; H2a/x; HIST5-2AX; Histone H2A.X; gamma H2A.X

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.

No documents available.