Phospho-HistoneH2B(T129) Rabbit Monoclonal Antibody

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Catalog Number:MABN83770
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from yeast Histone H2B.1 around the phosphorylation site of T129
Reactivity:Yeast
Applications:WB 1:1000-1:2000
Molecular Weight:14 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:HTB2; Htb2p; HTB1; Htb1p; Histone H2B.1; Histone H2B.2; SPT12;;p-Histone H2B.1 (T129)

Applications

WB 1:1000-1:2000

Immunogen

A synthesized peptide derived from yeast Histone H2B.1 around the phosphorylation site of T129

Target Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Synonyms:HTB2; Htb2p; HTB1; Htb1p; Histone H2B.1; Histone H2B.2; SPT12;;p-Histone H2B.1 (T129)

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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