Phospho-IGF1 Receptor (Tyr1166) Rabbit Monoclonal Antibody

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Catalog Number:MABN84866
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic phosphopeptide corresponding to residues surrounding Tyr1166 of human INSR/IGF-1R
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:1000,IP 1:10-1:20
Molecular Weight:Calculated MW: 155 kDa; Observed MW: 95 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221

Applications

WB 1:500-1:1000,IP 1:10-1:20

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Tyr1166 of human INSR/IGF-1R

Target Background

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

Synonyms:IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

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