Immunological Sciences

Phospho-Integrin alpha 4 (Ser1027)Rabbit Monoclonal Antibody

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Catalog Number:MABN87112
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic phosphopeptide corresponding to residues surrounding Ser1027 of human Integrin alpha 4
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000
Molecular Weight:Calculated MW:115 kDa; Observed MW:150,70 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:IA4; CD49D

Applications

WB 1:500-1:2000

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser1027 of human Integrin alpha 4

Target Background

The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

Synonyms:IA4; CD49D

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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