Phospho-JNK1 (Thr183/Tyr185) Rabbit Monoclonal Antibody
Western blot analysis of Phospho-JNK1 (Thr183/Tyr185) in Hela, A549, C6 lysates using Phospho-JNK1 (Thr183/Tyr185) antibody.
| Catalog Number: | MABN03804 |
| Conjugate: | Unconjugated |
| Size: | 100μL |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Clone: | Monoclonal |
| Immunogen: | A synthetic Phosphorylated peptide corresponding to residues target protein |
| Reactivity: | Human,Rat |
| Applications: | WB 1:500-1:1000,IP 1:20-1:50 |
| Molecular Weight: | 48 kDa |
| Purification: | Affinity purification |
| Form: | liquid |
| Synonyms: | c Jun N terminal kinase 1; C-JUN kinase 1; c-Jun N-terminal kinase 1; EC 2.7.11.24; JAK 1A; JAK1A; JNK 1; JNK 46; JNK; JNK-46; JNK1A2; JNK21B1/2; MAP kinase 8; MAPK 8; MAPK8; Mitogen activated protein kinase 8; |
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016]
Applications
WB 1:500-1:1000,IP 1:20-1:50
Immunogen
A synthetic Phosphorylated peptide corresponding to residues target protein