Phospho-LIM Kinase 1 (Thr508) Rabbit Polyclonal Antibody

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Catalog Number:ABN00951
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:A synthetic Phosphorylated peptide corresponding to residues target protein
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:100-1:200
Molecular Weight:Calculated MW: 73 kDa; Observed MW: 73 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:LIMK1; LIMK; LIM domain kinase 1; LIMK-1

Applications

WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:100-1:200

Immunogen

A synthetic Phosphorylated peptide corresponding to residues target protein

Target Background

Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Stimulates axonal outgrowth and may be involved in brain development. Isoform 3 has a dominant negative effect on actin cytoskeletal changes.

Synonyms:LIMK1; LIMK; LIM domain kinase 1; LIMK-1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

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