Immunological Sciences

Phospho-NF-kB p65 (Ser536) Rabbit Monoclonal Antibody

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Catalog Number:MABN87488
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic phosphopeptide corresponding to residues surrounding Ser536 of human NF-kB p65
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IP 1:20-1:50
Molecular Weight:Calculated MW:60 kDa; Observed MW:65 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:p65; NFKB3

Applications

WB 1:500-1:2000,IP 1:20-1:50

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser536 of human NF-kB p65

Target Background

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Synonyms:p65; NFKB3

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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