Phospho-p53 (Ser6) Rabbit Monoclonal Antibody

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Catalog Number:MABN84912
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic phosphopeptide corresponding to residues surrounding Ser6 of human p53
Reactivity:Human
Applications:WB 1:500-1:1000,IHC 1:50-1:100,IP 1:10-1:20
Molecular Weight:Calculated MW: 44 kDa; Observed MW: 53 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:TP53; P53; Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53

Applications

WB 1:500-1:1000,IHC 1:50-1:100,IP 1:10-1:20

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser6 of human p53

Target Background

Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains.

Synonyms:TP53; P53; Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

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