Phospho-Presenilin 1 (Ser310) Rabbit Monoclonal Antibody

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Catalog Number:MABN84836
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic phosphopeptide corresponding to residues surrounding Ser310 of human Presenilin 1
Reactivity:Human
Applications:WB 1:500-1:1000
Molecular Weight:Calculated MW: 53 kDa; Observed MW: 22 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:PSEN1; AD3; PS1; PSNL1; Presenilin-1; PS-1; Protein S182

Applications

WB 1:500-1:1000

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser310 of human Presenilin 1

Target Background

Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity.

Synonyms:PSEN1; AD3; PS1; PSNL1; Presenilin-1; PS-1; Protein S182

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

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