Phospho-Smad3 (Ser423/Ser425) Rabbit Monoclonal Antibody

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Catalog Number:MABN87151
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic phosphopeptide corresponding to residues surrounding Ser423/Ser425 of human Smad3
Reactivity:Human,Mouse
Applications:WB 1:500-1:2000,IHC 1:100-1:200,ICC/IF 1:100-1:200
Molecular Weight:Calculated MW:48 kDa; Observed MW:52 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:LDS3; LDS1C; MADH3; JV15-2; HSPC193; HsT17436

Applications

WB 1:500-1:2000,IHC 1:100-1:200,ICC/IF 1:100-1:200

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser423/Ser425 of human Smad3

Target Background

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. [provided by RefSeq, Apr 2009]

Synonyms:LDS3; LDS1C; MADH3; JV15-2; HSPC193; HsT17436

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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