Phospho-SMAD5 (Ser463/Ser465) Rabbit Monoclonal Antibody

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Catalog Number:MABN87435
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic phosphopeptide corresponding to residues surrounding Ser463/Ser465 of human SMAD5
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000
Molecular Weight:Calculated MW:52 kDa; Observed MW:60 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:DWFC; JV5-1; MADH5

Applications

WB 1:500-1:2000

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser463/Ser465 of human SMAD5

Target Background

The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

Synonyms:DWFC; JV5-1; MADH5

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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