Phospho-Src (Y419) (9I12) Rabbit Monoclonal Antibody

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Catalog Number:MABN06015
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic phosphopeptide corresponding to residues surrounding Tyr419 of human Src
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,FC 1:20-1:50
Molecular Weight:60kDa
Purification:Affinity purification
Form:Liquid
Synonyms:p60-Src; c-Src; pp60c-src; Avian sarcoma virus; Proto-oncogene c-Src; SRC Oncogene;

Applications

WB 1:500-1:2000,FC 1:20-1:50

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Tyr419 of human Src

Target Background

Non-receptor protein tyrosine kinase that plays pivotal roles in numerous cellular processes such as proliferation, migration, and transformation. In concert with PTK2B, plays an important role in osteoclastic bone resorption. Both the formation of a SRC-PTK2B complex, and SRC kinase activity are necessary for this function. Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein-coupled receptors as well as cytokine receptors.

Synonyms:p60-Src; c-Src; pp60c-src; Avian sarcoma virus; Proto-oncogene c-Src; SRC Oncogene;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

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