Immunological Sciences

Phospho-TAK1 (Ser439) Rabbit Monoclonal Antibody

No images available

Catalog Number:MABN87590
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic phosphopeptide corresponding to residues surrounding Ser439 of human TAK1
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IP 1:10-1:100
Molecular Weight:Calculated MW:67 kDa; Observed MW:78 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CSCF; FMD2; TAK1; MEKK7; TGF1a

Applications

WB 1:1000-1:5000,IP 1:10-1:100

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser439 of human TAK1

Target Background

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Synonyms:CSCF; FMD2; TAK1; MEKK7; TGF1a

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

No documents available.