Phospho-TAOK1/2/3(S181+S181+S177) Rabbit Monoclonal Antibody

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Catalog Number:MABN84763
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human TAOK 1/2/3 around the phosphorylation site of S181/S181/S177
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:2000,IHC 1:100-1:200
Molecular Weight:Calculated MW: 116 kDa ; Observed MW: 110,130,140 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:TAOK1; TAOK2; TAOK3;;p-TAOK 1/2/3 (S181/S181/S177)

Applications

WB 1:1000-1:2000,IHC 1:100-1:200

Immunogen

A synthesized peptide derived from human TAOK 1/2/3 around the phosphorylation site of S181/S181/S177

Target Background

Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. Phosphorylates MAP2K3, MAP2K6 and MARK2. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade by mediating phosphorylation and subsequent activation of the upstream MAP2K3 and MAP2K6 kinases. Involved in G-protein coupled receptor signaling to p38/MAPK14.

Synonyms:TAOK1; TAOK2; TAOK3;;p-TAOK 1/2/3 (S181/S181/S177)

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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