Phospho-YAP1 (Ser127) Rabbit Monoclonal Antibody

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Catalog Number:MABN87275
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic phosphopeptide corresponding to residues surrounding Ser127 of human YAP1
Reactivity:Human,Mouse,Rat
Applications:WB 1:2000-1:20000,IHC 1:100-1:200
Molecular Weight:Calculated MW:55 kDa; Observed MW:70-75 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:YAP; YKI; COB1; YAP2; YAP65

Applications

WB 1:2000-1:20000,IHC 1:100-1:200

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser127 of human YAP1

Target Background

This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]

Synonyms:YAP; YKI; COB1; YAP2; YAP65

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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