Immunological Sciences

PHOX2B (7H13) Rabbit Monoclonal Antibody

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Catalog Number:MABN16085
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human PHOX2B
Reactivity:Human,Mouse
Applications:WB 1:500-1:2000,IHC 1:200-1:1000,ICC/IF 1:100-1:200
Molecular Weight:32kDa
Purification:Affinity purification
Form:Liquid
Synonyms:NBLST2; NBPhox; PHOX 2B; PHOX2B; PMX 2B; PMX2B;

Applications

WB 1:500-1:2000,IHC 1:200-1:1000,ICC/IF 1:100-1:200

Immunogen

A synthetic peptide of human PHOX2B

Target Background

Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element. Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta- hydrolase and c-fos promoters, and of several enhancers including cAMP- response element and serum-response element.

Synonyms:NBLST2; NBPhox; PHOX 2B; PHOX2B; PMX 2B; PMX2B;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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