PI 3-kinase p85alpha
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| Catalog Number: | ABE8936 |
| Conjugate: | Unconjugated |
| Size: | 100ug |
| Concentration: | 1mg/ml |
| Host: | Rb |
| Isotype: | IgG |
| Clone: | POLY |
| Immunogen: | Synthesized peptide derived from PI 3-kinase p85α . at AA range: 550-630 |
| Reactivity: | Hu,Ms,Rt,Pig |
| Applications: | IF,WB,IHC,ELISA |
| Molecular Weight: | 54+83kD |
| Purification: | Affinity Purified |
| Form: | Liquid |
| Synonyms: | PIK3R1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alph |
Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011],
Applications
IF,WB,IHC,ELISA
Immunogen
Synthesized peptide derived from PI 3-kinase p85α . at AA range: 550-630