Immunological Sciences

PIDD1 Mouse Monoclonal Antibody

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Catalog Number:MABN82274
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human PIDD1 (AA: 776-910) expressed in E. Coli.
Reactivity:Human
Applications:ELISA 1:5000-1:20000
Molecular Weight:99.7kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:LRDD; PIDD

Applications

ELISA 1:5000-1:20000

Immunogen

Purified recombinant fragment of human PIDD1 (AA: 776-910) expressed in E. Coli.

Target Background

The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]

Synonyms:LRDD; PIDD

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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