Immunological Sciences

PIK3R1 Mouse Monoclonal Antibody

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Catalog Number:MABN81167
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human PIK3R1 (AA: 159-388) expressed in E. Coli.
Reactivity:Human,Mouse
Applications:IHC 1:200-1:1000,ICC 1:100-1:200,ELISA 1:5000-1:20000,FC 1:200-1:400
Molecular Weight:83.6kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:p85; GRB1; p85-ALPHA

Applications

IHC 1:200-1:1000,ICC 1:100-1:200,ELISA 1:5000-1:20000,FC 1:200-1:400

Immunogen

Purified recombinant fragment of human PIK3R1 (AA: 159-388) expressed in E. Coli.

Target Background

Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms.

Synonyms:p85; GRB1; p85-ALPHA

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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