PIM2 Rabbit Monoclonal Antibody

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Catalog Number:MABN03925
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human PIM2
Reactivity:Human, Mouse, Rat
Applications:WB 1:500-1:1000,IP 1:20-1:50
Molecular Weight:Calculated MW:34 kDa;Observed MW: 34-40 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:PIM2; Serine/threonine-protein kinase pim-2; Pim-2h

Applications

WB 1:500-1:1000,IP 1:20-1:50

Immunogen

A synthetic peptide of human PIM2

Target Background

Promotes cell survival in response to a variety of proliferative signals via positive regulation of the I-kappaB kinase/NF-kappaB cascade; this process requires phosphorylation of MAP3K8/COT. Prevents apoptosis induced by growth factor withdrawal via inhibition of caspase-3 activation, and via phosphorylation of pro-apoptotic proteins.

Synonyms:PIM2; Serine/threonine-protein kinase pim-2; Pim-2h

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

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