PIM2 Rabbit Monoclonal Antibody

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Catalog Number:MABN84410
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human PIM2
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:2000,ICC 1:50-1:200,IP 1:20-1:50
Molecular Weight:Calculated MW: 34 kDa ; Observed MW: 37 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:PIM2; Pim2h;;PIM2

Applications

WB 1:1000-1:2000,ICC 1:50-1:200,IP 1:20-1:50

Immunogen

A synthesized peptide derived from human PIM2

Target Background

Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression, the regulation of cap-dependent protein translation and through survival signaling by phosphorylation of a pro-apoptotic protein, BAD. Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase transcriptional activity.

Synonyms:PIM2; Pim2h;;PIM2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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