Immunological Sciences

PKM Rabbit Monoclonal Antibody

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Catalog Number:MABN87202
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human PKM
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:100-1:200
Molecular Weight:Calculated MW:58 kDa; Observed MW:58 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:PK3; TCB; p58; OIP3; PKM2; CTHBP; THBP1; HEL-S-30

Applications

WB 1:1000-1:5000,IHC 1:100-1:200

Immunogen

A synthetic peptide of human PKM

Target Background

This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011]

Synonyms:PK3; TCB; p58; OIP3; PKM2; CTHBP; THBP1; HEL-S-30

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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