PKR Rabbit Monoclonal Antibody

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Catalog Number:MABN86790
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human PKR
Reactivity:Human
Applications:WB 1:1000-1:5000,IHC 1:50-1:200,ICC/IF 1:20-1:50,FC 1:20-1:50,IP 1:20-1:100
Molecular Weight:Calculated MW:62 kDa; Observed MW:74 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:PKR; PRKR; EIF2AK1; PPP1R83

Applications

WB 1:1000-1:5000,IHC 1:50-1:200,ICC/IF 1:20-1:50,FC 1:20-1:50,IP 1:20-1:100

Immunogen

A synthetic peptide of human PKR

Target Background

The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Synonyms:PKR; PRKR; EIF2AK1; PPP1R83

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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