Immunological Sciences

Plasminogen Rabbit Monoclonal Antibody

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Catalog Number:MABN86959
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of mouse Plasminogen
Reactivity:Mouse
Applications:WB 1:500-1:2000,IP 1:20-1:50
Molecular Weight:Calculated MW:91 kDa; Observed MW:100 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Pg; AI649309

Applications

WB 1:500-1:2000,IP 1:20-1:50

Immunogen

Recombinant protein of mouse Plasminogen

Target Background

Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells (By similarity).

Synonyms:Pg; AI649309

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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