Immunological Sciences

Plexin A1 (3J3) Rabbit Monoclonal Antibody

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Catalog Number:MABN16268
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Plexin A1
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,FC 1:20-1:50
Molecular Weight:211kDa
Purification:Affinity purification
Form:Liquid
Synonyms:NOV; NOVP; Plexin-A1; Plexin1; PlexinA1; PLXN1; Plxna1;

Applications

WB 1:500-1:2000,FC 1:20-1:50

Immunogen

A synthetic peptide of human Plexin A1

Target Background

Plays a role in axon guidance, invasive growth and cell migration. Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity).

Synonyms:NOV; NOVP; Plexin-A1; Plexin1; PlexinA1; PLXN1; Plxna1;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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