Immunological Sciences

PLIN3 Mouse Monoclonal Antibody

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Catalog Number:MABN82942
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG2a
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human PLIN3 expressed in E. Coli.
Reactivity:Human
Applications:WB 1:500-1:2000,ICC 1:100-1:500,FC 1:200-1:400
Molecular Weight:47kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:PP17; TIP47; M6PRBP1

Applications

WB 1:500-1:2000,ICC 1:100-1:500,FC 1:200-1:400

Immunogen

Purified recombinant fragment of human PLIN3 expressed in E. Coli.

Target Background

Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms:PP17; TIP47; M6PRBP1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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